2015 Fiscal Year Final Research Report
Morphological evaluation of dentinal microcracks with human aging
| Project/Area Number |
25462956
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
Miura Jiro 大阪大学, 歯学部附属病院, 助教 (70437383)
Nishi Ryuji 大阪大学, 超高圧電子顕微鏡センター, 准教授 (40243183)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 象牙質 / 破折 / コラーゲン / 加齢 |
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| Outline of Final Research Achievements |
Several studies have investigated the effect of aging on the mechanism of crack propagation. They examined the cracked surface using scanning electron microscopy (SEM) to evaluate the structural modifications of dentinal microcracks with aging. Very few studies have utilized transmission electron microscopy (TEM) for sectional observation of microcracks. The purposed of this study were to morphologically evaluate the relation between dentinal microcrack propagation and human aging.
In young dentin, dentinal microcracks are propagated without interference in PTD. In contrast, in aged dentin, PTD is mature with hydroxyapatite, which prevents microcracks from propagating and they deflect around PTD. With this specimen fabrication method and TEM observation, it is possible to visualize ultra-structural propagation of microcracks within dentin, and evaluate dentinal microcrack propagation related to dentin microstructural modifications with aging.
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| Free Research Field |
保存修復
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