2016 Fiscal Year Final Research Report
A study of calcium sensing receptors in odontogenic tumors
| Project/Area Number |
25463088
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
|
| Keywords | 角化嚢胞性歯原性腫瘍由来線維芽細胞 / カルシウム感受性受容体 / BMP-2 |
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| Outline of Final Research Achievements |
The Fibroblasts isolated from odontogenic tumors express calcium sensing receptors. However, the precise function of the receptors is obscure. In this study, we showed that the expression of BMP-2 gene and protein was enhanced by calcium concentration dependent manner in the fibroblasts. These results may suggest the new methods for the bone formation by calcium which is cheep and safe.
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| Free Research Field |
口腔外科学
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