Development study of the nucleic acid innovative drug development for the chronic amyotrophy-related disease

2015 Fiscal Year Final Research Report

• Project/Area Number: 25463183
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthodontics/Pediatric dentistry
• Research Institution: The University of Tokushima
• Principal Investigator: KINOUCHI Nao 徳島大学, 大学病院, 助教 (30457329)
• Co-Investigator(Kenkyū-buntansha): TANAKA Eiji 徳島大学, 大学院医歯薬学研究部, 教授 (40273693) ; KAWAI Nobuhiko 徳島大学, 大学院医歯薬学研究部, 助教 (40437588)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: RNAi / 骨格筋

Outline of Final Research Achievements

We developed the liposome of the certainty of the security supply that it was cheaper, and a possible drug delivery system carrier for clinical application as a substitute of atelocollagen where the effectiveness was confirmed as a siRNA introduction agent. The possibility that it was effective for the adjustment of the local skeletal muscle mass in the individual level was suggested when we introduced myostatin specific siRNA which was a skeletal muscle mass suppressor with this liposome, and it was thought that we were connected for the development of the new cure for the chronicity hereditary muscular disorder in the future.

Free Research Field

矯正歯科