2017 Fiscal Year Final Research Report
The elucidation of the alveolar bone bone resorption mechanism in the eruption course formation of the tooth
| Project/Area Number |
25463194
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Iwate Medical University (2017)
Kyushu Dental College (2013-2016) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
牧 憲司 九州歯科大学, 歯学部, 教授 (60209400)
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| Project Period (FY) |
2013-04-01 – 2018-03-31
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| Keywords | 破骨細胞 / 歯槽骨 / 骨吸収 / 萌出 / 細胞接着 |
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| Outline of Final Research Achievements |
Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) are Ca2+ channels that localize to intracellular Ca2+ stores. Analysis of the experimental data strongly suggest IP3R type III may be related to regulation of an actin cytoskeleton in podosomes, actin-rich adhesion structures in osteoclasts and may be associated with the alveolar bone bone resorption.
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| Free Research Field |
小児歯学
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