2015 Fiscal Year Final Research Report
Development a new regenerative therapy and analysis of tissue regeneration / wound healing system by periodontal tissue stem cells
| Project/Area Number |
25463226
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Periodontology
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| Research Institution | Keio University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 歯周組織再生 / 間葉系幹細胞 / 神経堤細胞 / iPS細胞 |
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| Outline of Final Research Achievements |
（1）For the purpose of actual treatment, We have become possible to use human therapeutic iPS cells .
（2）In the future, We suppose the use of human therapeutic iPS cells . In practical application, it is very important problem to use the conventional culture system. Because these system use fetal bovine serum and non human feeder cell to culture of human iPS cells. To overcome these problems, we established non serum / non feeder culture system of human therapeutic iPS cells . We think these steps (feeder free / xeno free culture system)are very notable in this study.
（3）We succeeded inducing neural crest like cells from human iPS cells. Neural crest is developmental origin of periodontal tissue.
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| Free Research Field |
幹細胞生物学
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