Exploration of relevant factors of oral microbiome maturation by using molecular approach

2015 Fiscal Year Final Research Report

• Project/Area Number: 25463249
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Kyushu University
• Principal Investigator: Takeshita Toru 九州大学, 歯学研究科(研究院), 准教授 (50546471)
• Co-Investigator(Kenkyū-buntansha): YAMASHITA Yoshihisa 九州大学, 大学院歯学研究院, 教授 (20192403)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 口腔マイクロバイオーム / 16S rRNA / 舌苔 / 細菌

Outline of Final Research Achievements

This study revealed that compositional shift in tongue microbiome occurs during two years from birth. In particular, the relative abundances of dominant bacterial genera greatly changed after introduction of baby food (about 200 days from birth) in many of the subjects, implying that diet change would be a trigger of bacterial community succession. Our result would be the important basis for the establishment of a new approach for oral health promotion, which aims to induce healthy oral microbiome.

Free Research Field

予防歯科学