A cohort study for identifying risk factors of dental caries and periodontal disease

2015 Fiscal Year Final Research Report

• Project/Area Number: 25463275
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Ehime University (2014-2015); Fukuoka University (2013)
• Principal Investigator: TANAKA KEIKO 愛媛大学, 医学(系)研究科(研究院), 助教 (40341432)
• Co-Investigator(Kenkyū-buntansha): Miyake Yoshihiro 愛媛大学, 大学院医学系研究科, 教授 (50330246)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 疫学 / コホート研究 / う蝕 / 歯周病 / リスク要因

Outline of Final Research Achievements

The Kyushu Okinawa Maternal and Child Health Study (KOMCHS) is an ongoing prospective prebirth cohort study that investigates risk and preventive factors for maternal and child health problems such as oral health and allergic disorders.
Higher maternal vitamin D intake during pregnancy was associated with a lower risk of dental caries in children. Among young women, an inverse association between calcium intake and the prevalence of periodontal disease was observed. The heterozygous variant genotype of the IL1 rs16944 was associated a reduced risk of periodontal disease. No interaction of any of the IL1 polymorphisms with smoking was observed.

Free Research Field

医歯薬学