Exploring biomarker identification evaluating ecosystem fructuation in natural samples

2015 Fiscal Year Final Research Report

• Project/Area Number: 25513012
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: オミクス計測科学
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: Kikuchi Jun 国立研究開発法人理化学研究所, 環境資源科学研究センター, チームリーダー (00321753)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: NMR / 環境分析 / マイクロバイオーム / メタボローム / イオノーム / データサイエンス / 機械学習 / 共生システム

Outline of Final Research Achievements

Natural ecosystems can be conceptually thought of as interconnected environmental and metabolic systems. Humans and their activities affect and are a part of these ecosystems. Considering a more applied perspective of human activities within ecosystems, it is important to gain an understanding of natural ecology and its metabolic processes in various environments. We have shown the challenges of analytical approaches for molecular and microbial complexity in the ecosystem. The first challenge is macromolecular complexity to analyze structure and composition of polysaccharides. The second challenge is microbial complexity, namely concerning their metabolic activity. The third challenge is integrating molecular and microbial complexity, by using multi-omics approach. Our approach provides a foundation for evaluation of systemic effects of environmental fluctuation, and a step for opening up a new window that will clear up metabolic dynamics in the ecosystem.

Free Research Field

生命分析科学