Development of basic technology for privacy-preserving bioinformatics and its application

2015 Fiscal Year Final Research Report

• Project/Area Number: 25540131
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Life / Health / Medical informatics
• Research Institution: Waseda University (2014-2015); The University of Tokyo (2013)
• Principal Investigator: Hamada Michiaki 早稲田大学, 理工学術院, 准教授 (00596538)
• Co-Investigator(Kenkyū-buntansha): Shimizu Kana 早稲田大学, 理工学術院, 准教授 (60367050)
• Co-Investigator(Renkei-kenkyūsha): Hanaoka Goichiro 独立行政法人産業技術総合研究所, 研究グループ長 (30415731) ; Tsuda Koji 東京大学, 大学院新領域創成科学研究科, 教授 (90357517) ; Frith Martin 産業技術総合研究所, 人工知能研究センター, 主任研究員 (40462832) ; Asai Kiyoshi 東京大学, 大学院新領域創成科学研究科, 教授 (30356357)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: プライバシー保護 / 化合物検索 / アラインメント / 隠れマルコフモデル

Outline of Final Research Achievements

It is highly demanded to deal with the information of personal genome and chemical compound secretly, because they are sensitive information that should not be leaked. On the other hand, from a viewpoint of "open" science, it is important to perform data-mining by combining those sensitive information with other data. In this study, we have developed several methods to perform data-mining, making those information secret. Specifically, we developed (i) privacy-preserving search for chemical database, (ii) privacy-preserving genome sequence search with hidden Markov Model (HMM) and (iii) privacy preserving sequence alignment, all of which will be useful toward open science of biology.

Free Research Field

バイオインフォマティクス