2015 Fiscal Year Final Research Report
Visualization of comformational changes of a chromoprotein.
Project/Area Number |
25560069
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Science education
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Research Institution | Saitama University |
Principal Investigator |
|
Project Period (FY) |
2013-04-01 – 2016-03-31
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Keywords | 蛋白質 / 構造変化 / 色素蛋白質 / 可視化 / 遅延化 / 教材化 |
Outline of Final Research Achievements |
Proteins change their structures when they function. The rate of the structural changes are too fast to see. A cylcle of conformational changes of a purple-colored chromoprotein, bacteriorhodopsin(bR) occurs rapidly in 10 ms. This structural transition accompanys a series of intermediates with distinctive colors. A mutation on bR with single amino acid substitution made the cyclic changes slower enough to see by our eyes.
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Free Research Field |
蛋白質化学
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