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2015 Fiscal Year Final Research Report

Visualization of comformational changes of a chromoprotein.

Research Project

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Project/Area Number 25560069
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Science education
Research InstitutionSaitama University

Principal Investigator

TOMIOKA Hiroaki  埼玉大学, 教育学研究科, 教授 (50212072)

Project Period (FY) 2013-04-01 – 2016-03-31
Keywords蛋白質 / 構造変化 / 色素蛋白質 / 可視化 / 遅延化 / 教材化
Outline of Final Research Achievements

Proteins change their structures when they function.  The rate of the structural changes are too fast to see. A cylcle of conformational changes of a purple-colored chromoprotein, bacteriorhodopsin(bR) occurs rapidly in 10 ms. This structural transition accompanys a series of intermediates with distinctive colors. A mutation on bR with single amino acid substitution made the cyclic changes slower enough to see by our eyes.

Free Research Field

蛋白質化学

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Published: 2017-05-10  

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