Electric device which interfaces heart to regenerated cardiac tissue derived from iPS cells

2015 Fiscal Year Final Research Report

• Project/Area Number: 25560197
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: Osaka University
• Principal Investigator: YAGI Tetsuya 大阪大学, 工学(系)研究科(研究院), 教授 (50183976)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 再生医療 / 組織培養 / iPS細胞 / 電子デバイス / インターフェイス / 神経 / 筋

Outline of Final Research Achievements

To reconstruct the function of disordered excitable organs with implantation of cultured tissues, an electrical device is needed to interface the activities of the host organ to the implanted tissue. We have developed a multi-channel programmable integrated system that can electrically stimulate the tissue during the culture. The system can deliver currents at a high precision and with various spatio-temporal patterns to effectively control the activity of the cultured tissue. The system is compact and can be installed to a microscope, which allows a long term experiment duirng the culture.

Free Research Field

生体医工学