Preparation of the propulsion engine-loaded nanoparticle and evaluation of its tissue permeability

2014 Fiscal Year Final Research Report

• Project/Area Number: 25560223
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: Osaka University
• Principal Investigator: BABA Koichi 大阪大学, 医学(系)研究科(研究院), 寄附講座准教授 (00436172)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: ナノバイオ材料 / 点眼液 / ナノ粒子薬剤

Outline of Final Research Achievements

Generally, it is recognized that the ocular penetration rate of eye drops into ocular globe is comparably low. This is because several barrier functions exist in ocular globe. Furthermore, we considered that the only the passive diffusion energy after eye drop administration is not enough for drug penetration into ocular globe. In this study we tried to prepare drug nanoparticle eye drops which has propulsion engine inside nanoparticles.

Free Research Field

有機ナノ材料化学