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2016 Fiscal Year Final Research Report

The effects of environmental stresses of high-altitude (i.e., hypoxia and hypothermia) on activation of brown adipose tissue and anti-obesity.

Research Project

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Project/Area Number 25560380
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionRitsumeikan University

Principal Investigator

Taguchi Sadayoshi  立命館大学, 総合科学技術研究機構, 教授 (90086819)

Project Period (FY) 2013-04-01 – 2017-03-31
Keywords高所 / 低酸素 / 脂質代謝 / 脂肪蓄積 / 肥満
Outline of Final Research Achievements

This study was conducted to examine the effects of hypoxia and hypothermia on fat metabolism by focusing on UCP1 (Uncoupling protein 1), which is related to brown adipose tissue. We found that hypoxia might not influence the UCP1 expression, while it may inhibit the lipogenesis, thereby reducing the lipid storage in adipocytes.

Free Research Field

運動生理学

URL: 

Published: 2018-03-22  

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