Identification points of toxic yellow Tricholoma species which causes rhabdomyolysis

2016 Fiscal Year Final Research Report

• Project/Area Number: 25560409
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biomolecular chemistry
• Research Institution: Keio University (2014-2016); Kyoto Pharmaceutical University (2013)
• Principal Investigator: Hashimoto Kimiko 慶應義塾大学, 理工学部(矢上), 特任准教授 (90286641)
• Research Collaborator: MORIMOTO Shigeo
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: キシメジ / シモコシ / カラキシメジ / 見分け方 / 分類同定 / 横紋筋融解症

Outline of Final Research Achievements

Mushroom poisoning caused by Tricholoma equestre developed fatal rhabdomyolysis both in France and Poland. The T. equestre is a synonym of T. flavovirens known to distribute in Japan. In order to study the toxic principle of this mushroom, discrimination of this fungus from some similar species is essential.
For this purpose, the most complicated problem is absence of definite morphological information of each resembling fungi distribute in Japan. On investigation of possible Tricholoma species, discrimination of the following three yellow species, T. flavovirens, T. auratum, and T. aestuans was turned out to be the critical point. A kind of the host trees helps the discrimination, that is, T. auratum and T. aestuans grow in a coniferous forest, on the other hand, T. flavovirens do not depend on coniferous trees and grows in a broadleaf forest. Taste of the carpophore is another clue, that is, T. aestuans has a bitter taste and then produce a sharp taste on chewing.

Free Research Field

天然物化学