2013 Fiscal Year Final Research Report
Next generation photostimulation system using tunable laser
| Project/Area Number |
25560423
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Basic / Social brain science
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| Research Institution | Saitama University |
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Principal Investigator |
NAKAI Junichi 埼玉大学, 脳科学融合研究センター, 教授 (80237198)
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| Co-Investigator(Renkei-kenkyūsha) |
ANDO Keiko 埼玉大学, 脳科学融合研究センター, 特任准教授 (40221741)
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| Project Period (FY) |
2013-04-01 – 2014-03-31
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| Keywords | オプトジェネティクス / 光遺伝学 / KTN結晶 / 第二高調波発生 |
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| Research Abstract |
In this study we developed a tunable wavelength photo-stimulation equipment. We could generate second harmonic waves ranging from ~400 nm to ~500 nm with a fun-out type periodically polarized crystal. So this equipment can photo-stimulate GFP, channelrhodopsin, and many other photosensitive molecules. In the system we also equipped a pair of potassium tantalate niobate (KTN) crystals as a tunable lens, an electro-optic device that changes its refractive index by voltage. By changing the voltage which applied to the tunable KTN lens, focus changed within ~20 microseconds. The speed of focus change was about 500~1000 times faster than that of the conventional piezo focuser. This technique can be applicable not only to scientific researches including brain science but also industrial field such as laser processing and laser measurement.
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Research Products
(19 results)
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[Journal Article] Pretreatment of donor islets with the Na+/Ca2+ exchanger inhibitor improves the efficiency of islet transplantation2013
Author(s)
Mera T, Itoh T, Kita S, Kodama S, Kojima D, Nishinakamura H, Okamoto K, Ohkura M, Nakai J, Iyoda T, Iwamoto T, Matsuda T, Baba A, Omori K, Ono J, Watarai H, Taniguchi M, Yasunami Y
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Journal Title
Am J Transplantation
Volume: 13
Pages: 2154-2160
DOI
Peer Reviewed
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[Presentation] Hippocampal CA1 network dynamics during locomotion in virtual reality2013
Author(s)
Sato M, Mizuta K, Kawano M, Takekawa T, Islam T, Yamakawa H, Yamaguchi Y, Fukai T, Ohkura M, Nakai J, Hayashi Y
Organizer
Neuroscience2013
Place of Presentation
San Diego(USA)
Year and Date
20131109-13
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[Presentation] 生体における海馬神経回路活動の可視化2013
Author(s)
佐藤正晃, 水田恒太郎, 河野真子, 竹川高志, イスラムタンビル, 山川宏, 山口陽子, 深井朋樹, 大倉正道, 中井淳一, 林康紀
Organizer
第36回日本神経科学大会
Place of Presentation
京都国際会館
Year and Date
20130620-23
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[Presentation] 二次運動野からのトップダウン入力による体性感覚の制御, 36回日本神経科学大会2013
Author(s)
真仁田聡, 鈴木崇之, 松元崇, 本間千尋, 山田一之, 太田桂輔, 小田川摩耶, 松原智恵, 大倉正道, 佐藤正晃, 中井淳一, 林康紀, ラーカムマシュー, 村山正宜
Organizer
36回日本神経科学大会
Place of Presentation
京都国際会館
Year and Date
20130620-23
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