2015 Fiscal Year Final Research Report
Computerized model building of brain neuronal network
| Project/Area Number |
25610126
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biological physics/Chemical physics/Soft matter physics
|
|---|
| Research Institution | Tokai University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
TAKEKOSHI Susumu 東海大学, 医学部, 教授 (70216878)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | 神経回路 / マイクロCT |
|---|
| Outline of Final Research Achievements |
Brain is composed of a huge number of neurons, which constitute neuronal circuits. The first step to analyzing such brain circuits is to trace neuronal networks to build three-dimensional models of their complicated structures. In this study, we have developed methods for building three-dimensional wire models by tracing neuronal networks. We evaluated a number of algorithms reported for tracing wire-form structures in two-dimensional images. Some of those methods were proven to be effective in the computerized building of neuronal network model. A part of this study has been published as a feature article of the September 2015 issue of Microscopy Today, the official publication of the Microscopy Society of America.
|
| Free Research Field |
構造生物学
|
