Development of Advanced Molecular Transformations by 'Organobase/Chiral Lewis Acid' Concerted Binary Catalytic System

2015 Fiscal Year Final Research Report

• Project/Area Number: 25620073
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Synthetic chemistry
• Research Institution: Tohoku University
• Principal Investigator: TERADA Masahiro 東北大学, 理学(系)研究科(研究院), 教授 (50217428)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 不斉合成 / 触媒 / 有機塩基 / 物質変換 / 環境調和 / 反応場

Outline of Final Research Achievements

The purpose of this study is the development of concerted binary catalytic system which combines activation of reactant by organobase and stereocontrol by chiral Lewis acid. The proposed system is aimed at the design of the chiral art complex to realize highly stereoselective transformations, where two type of catalytic system was investigated. 1) In the development of organobase/chiral metal phosphate salts concerted binary catalytic system, combination of organobase and alkaline earth metal or rare earth metal salts as a central metal species were investigated. 2) In the development of organobase/chiral Schiff base metal salt concerted binary catalytic system, combination of organobase and alkaline metal salts as a central metal species was investigated.

Free Research Field

有機化学