2013 Fiscal Year Research-status Report
ナノキャビティの表面プラズモン閉じ込め効果を用いた疾病センサーの開発
| Project/Area Number |
25630019
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Research Institution | The University of Tokyo |
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Principal Investigator |
J・J Delaunay 東京大学, 工学(系)研究科(研究院), 准教授 (80376516)
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| Co-Investigator(Kenkyū-buntansha) |
田畑 仁 東京大学, 工学(系)研究科(研究院), 教授 (00263319)
藤川 茂紀 九州大学, カーボンニュートラル・エネルギー国際研究所, 准教授 (60333332)
前田 悦男 東京大学, 工学(系)研究科(研究院), 助教 (60644599)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | ナノマイクロ加工 / メタマテリアル・表面プラズモン |
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| Research Abstract |
The purpose of the research project is to demonstrate a small-size and low-cost sensor for the early diagnosis of diseases. A very sensitive detection technique of biomarkers should be developed using confined surface plasmons in nano-cavities operating on small sample volumes.
In the first year of the research project, we focused on the detection mechanism using confined surface plasmons in nanocavities. We found that perfect light confinement in nano-cavities is possible when high-aspect-ratio U-shaped cavities are used to couple the cavity ridge hot spots with the scalable U-cavity resonances. Under the condition of coupled resonance, light is fully trapped in intense optical vortices and confined on the extended U-shaped cavity surfaces, thus accumulating energy in tunable and strong resonances with narrow bandwidths. This strong resonance generates sensitive reflectance dips. The wavelength of the reflectance dip is readily controlled over a wide range of wavelengths covering the near-infrared region by varying the geometrical parameters of the U-cavities. The light confinement in the nano-cavity is realized for a finite number of adjacent nano-cavities, so that a small size detector operating on small sample volume is possible.
The reported full light confinement in the nano-cavities observed by a strong and sharp resonance has potential for applications in various optical devices such as filters, transducers and switches.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
In the first year of this research project, we should have clarified the mechanism of light confinement in the proposed nano-cavities and applied this knowledge to the design of the nano-cavities for biomaterial sensing. The mechanism of light trapping in the nano-cavities was described in our recent publication [Advanced Optical Materials DOI: 10.1002/adom.201400145]. We show that light is confined in the nano-cavities by coupling plasmonic modes to scalable cavity modes and, therefore, the resonance of the nano-cavites can be controlled by varying the geometrical parameters of the cavities. This property enables tuning of the nano-cavity resonance wavelength in the near infrared region in which detection of biomaterials is most efficient. Finally, we fabricated the designed nanocavities and obtained a good agreement between the simulated properties of the designed nano-cavities and the fabricated nano-cavities.
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| Strategy for Future Research Activity |
In the second year, the sensitivity of the proposed U-shaped nano-cavities will be quantified in terms of the shift in the resonance wavelength. The change in the wavelength of the resonance reflectance dip of the nano-cavities will be first investigated by varying the refractive index of the surrounding of the nano-cavities. Moreover, the ability of the nano-cavities to detect biomarkers will be tested using a protein ligand scheme by observing the change in the resonance wavelength upon the selective attachment of proteins on the nano-cavity surfaces.
Finally a design enabling low-cost fabrication of the sensitive cavity structure will be proposed and tested.
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[Patent(Industrial Property Rights)] 光学素子2014
Inventor(s)
Y-L Ho, JJ Delaunay
Industrial Property Rights Holder
Y-L Ho, JJ Delaunay
Industrial Property Rights Type
特許
Industrial Property Number
特願2014-015066
Filing Date
2014-01-30
