2016 Fiscal Year Final Research Report
The roles of non-coding RNAs on neural differentiaton of human ESCs/iPSCs
| Project/Area Number |
25640038
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | Aichi Medical University (2014-2016)
Keio University (2013) |
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Principal Investigator |
Okada Yohei 愛知医科大学, 医学部, 准教授 (30383714)
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| Co-Investigator(Renkei-kenkyūsha) |
MIYA Fuyuki 東京医科歯科大学, 難治疾患研究所, 助教 (50415311)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | ヒトES細胞 / ヒトiPS細胞 / ノンコーディングRNA / 神経分化 |
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| Outline of Final Research Achievements |
Several non-coding RNAs (ncRNAs) upregulated during neural differentiation of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) were identified by genome-wide transcriptome analysis. In addition, methods for the analysis of identified ncRNAs during neural differentiation of human ESCs were also established.
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| Free Research Field |
分子神経生物学
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