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2015 Fiscal Year Final Research Report

Establish of rapid and efficient blood cell differentiation

Research Project

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Project/Area Number 25640044
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Laboratory animal science
Research InstitutionThe University of Tokyo

Principal Investigator

Yamazaki Satoshi  東京大学, 医科学研究所, 助教 (50625580)

Project Period (FY) 2013-04-01 – 2016-03-31
Keywords造血幹細胞 / 免疫細胞 / 血液細胞 / 蛍光タンパク質
Outline of Final Research Achievements

Labeling each differentiation lineage cells of the hematopoietic stem cells and immune cells were considered an important tool for rapid and convenient analysis method using the mouse. We had hypothesized that able to analyze the blood cell differentiation by using the HAC technology. We have to explore the specific genes of each differentiated cells at the beginning. A variety of fluorescent proteins were identified the optimal combination of fluorescent proteins by gene introduced into the cell. However, although the artificial chromosome technology did not meet the deadline, you want to be successful establishment of mice to continue in the future.

Free Research Field

幹細胞生物学

URL: 

Published: 2017-05-10  

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