2014 Fiscal Year Final Research Report
Analysis of the mechanisms of process burdens in yeast
| Project/Area Number |
25640115
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
System genome science
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| Research Institution | Okayama University |
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Principal Investigator |
HISAO Moriya 岡山大学, 異分野融合先端研究コア, 准教授 (60500808)
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| Co-Investigator(Kenkyū-buntansha) |
KITO Keiji 明治大学, 農学部, 講師 (40345632)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 酵母 / タンパク質過剰 / プロセス負荷 / 局在化 |
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| Outline of Final Research Achievements |
Strong expression of a protein in a cell sometimes causes cellular defects. However, it is not systematically understood the mechanisms causing the defects. In this study, we discovered that the strong expression of proteins localized to intracellular compartments caused cellular defects due to the burdens for protein localization processes themselves.
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| Free Research Field |
システム生物学
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