A pilot study for elucidating molecular mechanisms regulating sexual dimorphism and diversity of human and non-human primates

2014 Fiscal Year Final Research Report

• Project/Area Number: 25650154
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Physical anthropology
• Research Institution: Kitasato University
• Principal Investigator: OOTA Hiroki 北里大学, 医学部, 准教授 (40401228)
• Co-Investigator(Kenkyū-buntansha): FURUICHI Takeshi 京都大学, 霊長類研究所, 教授 (20212194)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 性的二型 / ニホンザル / 排卵 / 発情期 / エストロゲン / プロゲステロン / 遺伝子発現 / RNAseq

Outline of Final Research Achievements

[Purpose] In this study, we try to provide a list of the genes that change the expression levels in phase with oscillation of sex hormones. [Materials&Methods] Blood samples were collected from two Japanese macaques with spontaneous ovulation. The blood concentrations of estradiol and progesterone were measured with time. We extracted RNAs from the blood at the peaks of the hormone concentrations just before and after ovulation, and conducted RNAseq for the four samples. [Progress] We are going to analyze the raw data of RNAseq.

Free Research Field

ゲノム人類学