2013 Fiscal Year Final Research Report
Comprehensive analysis of glycerol metabolism in archaea
| Project/Area Number |
25660056
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied microbiology
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| Research Institution | Osaka University |
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Principal Investigator |
KOGA Yuichi 大阪大学, 工学(系)研究科(研究院), 准教授 (30379119)
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| Project Period (FY) |
2013-04-01 – 2014-03-31
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| Keywords | 古細菌 / 超好熱菌 / 始原菌 / グリセロール代謝 |
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| Research Abstract |
Recently, we have found that the glycerol metabolic pathway of a hyperthermophilic archaeon, Thermococcus kodakarensis KOD1, is quite simple to compare with those of other organisms. Also the regulation of the glycerol metabolism was found to be independent from the central metabolic pathway. Through the cultivation test of deletion mutant of three genes of glycerol metabolism and the further biochemical analysis of each product of those genes, glycerol is not used as the carbon source but used for cell adaptation to oxygen stress and osmotic stress in T. kodakarensis KOD1.
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