2015 Fiscal Year Final Research Report
GnRH signals in female mice induce male sexual behaviors via vomeronasal organs of males
| Project/Area Number |
25660251
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Integrative animal science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OHATA Motoko 北里大学, 獣医学部, 助教 (60453510)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 繁殖行動 / GnRH / 性フェロモン / エストロジェン |
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| Outline of Final Research Achievements |
When GnRH mutant (hpg) female mice were treated with estrogen and intra cerebrum GnRH, they were significantly chased by normal male mice. These changes were not observed in vomeonasal organ-removed male mice. There were several specific peaks in the urea of the estrogen and GnRH treated hpg mice. These findings suggest that female cerebral GnRH stimulates male sexual behaviors via the male vomeonasal organ and it is mediated by some kind of chemical in mice.
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| Free Research Field |
獣医生理学
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