2014 Fiscal Year Final Research Report
Approach to develop a dynamics control technology of nanomaterial for oral nano-vaccine carrier
Project/Area Number |
25670075
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Medical pharmacy
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Research Institution | Osaka University |
Principal Investigator |
TSUTSUMI Yasuo 大阪大学, 薬学研究科(研究院), 教授 (50263306)
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Project Period (FY) |
2013-04-01 – 2015-03-31
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Keywords | 経口ワクチン / 新興再興感染症 |
Outline of Final Research Achievements |
In this study, by the foundation of our own linkage information between physical properties of nanomaterials and the information of dynamics, we attempted to analyze the kinetics of antigen-nanoparticles that are not given a hand though it is most important thing for development of vaccine. From this study, we tried to collect the fundamental information toward the establishment of Japanese originated nano-vaccine. In the future, accumulation of linkage information of various nanomaterials with their dynamics might result in development of nano-carrier that can transport the antigen from the mouth to the immunocompetent cells, and that can induce mucosal immunity effectively and safety.
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Free Research Field |
ナノ安全科学、薬物動態学、薬物送達学
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