Circulation physiology of continuous flow with artificial heart

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670105
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: General physiology
• Research Institution: The University of Tokyo
• Principal Investigator: INOUE Yusuke 東京大学, 工学(系)研究科(研究院), 研究員 (80611079)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 微小循環 / 循環生理学 / 末梢循環 / 循環調節 / 顕微鏡 / 体内埋込 / 人工心臓 / 駆動方式

Outline of Final Research Achievements

We developed microscope for micro circulation. We developed 3 type devices. The observation microscope has scaffold for angiogenesis. The PGA fabric and polyester fabric was used as scaffolds. And we get stable data with this device. We experiment with Total Artificial Heart. The animal with artificial heart living, and we observed our observation device. We change the heart drive pattern, exercise stress test, dose a medicine. We analyze the data. We found the difference of flow in the micro circulation via pattern of artificial heart moving.

Free Research Field

医工学・生理学