2015 Fiscal Year Final Research Report
Investigation of the structuring of vasculogenic mimicry in rheumatoid arthritis synovium for novel therapy.
| Project/Area Number |
25670262
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied pharmacology
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| Research Institution | Teikyo University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 擬似血管 |
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| Outline of Final Research Achievements |
The structuring of vasculogenic mimicry (VM) is unknown in rheumatoid arthritis synovium. I propose the hypothesis that VM participates in disease malignancy of rheumatoid arthritis as well as cancer malignancy. And then, I focus on VM in rheumatoid arthritis synovium as the novel therapeutic target for rheumatoid arthritis. I investigated whether VM was assembled in rheumatoid arthritis synovium. The results suggested that VM was assembled in rheumatoid arthritis synovium of both human and mouse.
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| Free Research Field |
がん免疫
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