Prospective cohort study on the relationship between genetic and environmental factors and perinatal depressive symptoms

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670305
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Epidemiology and preventive medicine
• Research Institution: Ehime University (2014); Fukuoka University (2013)
• Principal Investigator: MIYAKE Yoshihiro 愛媛大学, 医学(系)研究科(研究院), 教授 (50330246)
• Co-Investigator(Kenkyū-buntansha): TANAKA Keiko 愛媛大学, 大学院医学系研究科, 助教 (40341432)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 出生前コーホート研究 / 栄養 / 妊娠中うつ症状 / 有症率 / 横断研究 / 魚介類 / 乳製品 / 海草

Outline of Final Research Achievements

Using baseline data from the Kyushu Okinawa Maternal and Child Health Study, a prebirth cohort study, we investigated the relationships maternal intake and depressive symptoms during pregnancy. Study subjects were 1745 pregnant women. Depressive symptoms were defined as present when subjects had a Center for Epidemiologic Studies Depression Scale score of 16 or higher. The prevalence of depressive symptoms during pregnancy was 19.3%. Higher consumption levels of fish, eicosapentaenoic acid, docosahexaenoic acid, yogurt, calcium, seaweed, and vitamin D were significantly associated with a lower prevalence of depressive symptoms during pregnancy. On the other hand, higher intake levels of total fat and saturated fatty acids were significantly related to a higher prevalence of depressive symptoms during pregnancy.

Free Research Field

疫学・予防医学