2014 Fiscal Year Final Research Report
Analysis of pancreatitis-associated gene variation by next-generation sequencing
| Project/Area Number |
25670363
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Gastroenterology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MASAMUNE Atsushi 東北大学, 大学院医学系研究科, 准教授 (90312579)
KUME Kiyoshi 東北大学, 大学病院, 助教 (30431563)
HAMADA Shin 東北大学, 大学院医学系研究科, 助教 (20451560)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 次世代シークエンス / 膵炎関連遺伝子 |
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| Outline of Final Research Achievements |
We performed comprehensive analysis of gene variation in CFTR gene using next-generation sequencing. Total 10 non-synonymous and 6 synonymous variants were identified. Among them, the frequency of the c.4056G>C (p.Q1352H) variant was higher in patients with chronic pancreatitis.
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| Free Research Field |
医歯薬学
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