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2014 Fiscal Year Final Research Report

Cloning of non-dystrophin transcript from the dystrophin gene

Research Project

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Project/Area Number 25670480
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Pediatrics
Research InstitutionKobe Gakuin University

Principal Investigator

MATSUO Masafumi  神戸学院大学, 総合リハビリテーション学部, 教授 (10157266)

Co-Investigator(Renkei-kenkyūsha) TAKESHIMA Yasuhiro  兵庫医科大学, 医学部, 教授 (40281141)
Project Period (FY) 2013-04-01 – 2015-03-31
Keywordsジストロフィン遺伝子 / クローニング / 内在遺伝子 / ウェスターンブット
Outline of Final Research Achievements

A novel transcript from the central part of the dystrophin gene was cloned. From the elucidated amino acid sequence, an antibody was produced and used for immunostaining of human tissues. Immunoreactive materials were detected in several human tissues. Especially、immunoreactive material was identified in urine sample.

Free Research Field

内科系・臨床医学 小児科学

URL: 

Published: 2016-06-03  

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