Development of a PET/Cerenkov-light hybrid imaging system

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670529
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Nagoya University
• Principal Investigator: SEIICHI Yamamoto 名古屋大学, 医学(系)研究科(研究院), 教授 (00290768)
• Co-Investigator(Renkei-kenkyūsha): HATAZAWA Jun 大阪大学, 医学系研究科, 教授 (70198745) ; WATABE Hiroshi 東北大学, サイクロトロンラジオアイソトープセンター, 准教授 (40280820)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: PET / チェレンコフ光 / 同時測定

Outline of Final Research Achievements

We developed and tested a PET/Cerenkov-light hybrid imaging system. The PET/Cerenkov-light hybrid imaging system consists of a dual head PET system, reflection mirror located upper side of the subject and a high sensitivity CCD camera. These systems are installed inside a black box for imaging the Cerenkov-light. The spatial resolution of the Cerenkov-light imaging system was ~200um for Na-22 point source. Using the combined PET/Cerenkov-light imaging system, we could successfully obtain fused images with simultaneously acquired images. The distributions of the images are sometimes different from each other due to the light transmission in the body of the subject in Cerenkov-light images. We conclude that the developed PET/Cerenkov-light hybrid imaging system is useful to evaluate the merit and limitation of the Cerenkov-light imaging in molecular imaging.

Free Research Field

医学物理