Intraoperative computer-aided pathological diagnosis of lung cancer using the device for ultrarapid immunohistochemical staining method developed in our institute.

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670605
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Respiratory surgery
• Research Institution: Akita University
• Principal Investigator: MINAMIYA Yoshihiro 秋田大学, 医学(系)研究科(研究院), 教授 (30239321)
• Co-Investigator(Kenkyū-buntansha): AKAGAMI Yoichi 秋田県産業技術センター, 副所長 (00373217) ; NANJO Hiroshi 秋田大学, 医学部, 准教授 (70250892)
• Research Collaborator: KAWAGUCHI Haruma ; TERATA Kaori ; NAKAMURA Ryuta
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 術中迅速病理診断 / 免疫組織染色 / 自動診断

Outline of Final Research Achievements

Intraoperative pathological diagnosis is required for the surgical treatment of cancer patients. However, a shortage of pathologists is serious in Japan. The aim of this study is the establishment of the intraoperative computer-aided pathological diagnosis. We have developed a equipment to complete immunohistochemical staining within 20 minutes. We tried to develop the intraoperative computer-aided pathological diagnosis after staining the sample using this equipment. The index of the objective evaluation is required for the intraoperative computer-aided pathological diagnosis. There are two types of positive control. One is in the morphological control, is another the concentration control. The index of the target protein concentration was made of polymer of the microhydrogel containing the target protein. The morphological index was made of the cultured cells.

Free Research Field

外科学