2014 Fiscal Year Final Research Report
Analysis of expression of Cd antigens in retinoblastoma, and its application for disease classification and therapeutic strategy
| Project/Area Number |
25670726
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 網膜 / 腫瘍 / 表面抗原 |
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| Outline of Final Research Achievements |
Retinoblastoma is the most frequent cancer in the eye. Retinoblastoma showed different pathological types, but there is no classification based on knowledge of gene information such as mutation, or translocation. Cell surface antigens are proteins that expressed in cell surface, and can be used for identification and purification of certain subset of cells. We analyzed expression pattern of Cd antigens in patient derived retinoblastoma clinical samples, and found that different expression patterns of Cd antigens in different pathological featured retinoblastoma. These results suggested information of expression pattern of Cd antigens can be used for diagnosis and planning of therapeutic strategy,
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| Free Research Field |
分子生物学
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