Development of treatment for occlusal dysethesia with botulinum toxin

2015 Fiscal Year Final Research Report

• Project/Area Number: 25670821
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: The University of Tokushima
• Principal Investigator: MATSUKA Yoshizo 徳島大学, 大学院医歯薬学研究部, 教授 (90243477)
• Co-Investigator(Kenkyū-buntansha): KAJI Ryuji 徳島大学, 大学院医歯薬学研究部, 教授 (00214304) ; SHIGEMOTO Shuji 徳島大学, 大学院医歯薬学研究部, 助教 (20294704) ; SUZUKI Yoshitaka 徳島大学, 大学院医歯薬学研究部, 助教 (40581393) ; OKURA Kazuo 徳島大学, 大学院医歯薬学研究部, 講師 (70304540) ; TAKEUCHI Hisahiro 徳島大学, 病院, 講師 (10222093)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 咬合感覚異常 / ボツリヌス毒素 / ブラキシズム / 口腔顔面痛

Outline of Final Research Achievements

Occlusal dysethesia patient (1. complain occlusal contact abnormality at central occlusion more than 6 months, 2. patient can point the problem tooth) who agreed the boltulinum toxin treatment was injected botulinum toxin after masseter muscle activity recording. The occlusal abnormal sensation was measured with Visual Analogue Scale（VAS）. After boltulinum toxin injection, orofacial pain was decreased but occlusal dysethesia sensation was not decreased significantly.

Free Research Field

補綴・理工系歯学