Development of artificial saliva-secreting automated device placed inside the mouth activated by oral environment and functional activities

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670889
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Social dentistry
• Research Institution: Tohoku University
• Principal Investigator: KOSEKI Takeyoshi 東北大学, 歯学研究科(研究院), 教授 (80291128)
• Co-Investigator(Kenkyū-buntansha): HOSOKAWA Ryoichi 東北大学, 大学院歯学研究科, 准教授 (40547254) ; TANDA Naoko 東北大学, 病院, 助教 (00422121) ; YOSHIDA Eiko 東北大学, 病院, 医員 (40648458) ; ITO Emi 東北大学, 大学院歯学研究科, 技術専門職員 (80596817)
• Co-Investigator(Renkei-kenkyūsha): NISHIHARA Tatsuji 九州歯科大学, 歯学研究科, 教授 (80192251)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 唾液 / 口腔内環境 / 運動 / 分泌 / 人工唾液

Outline of Final Research Achievements

Saliva has important roles in maintaining the environment of the healthy mouth and in supporting the smooth activities of many oral functions in daily lives. When the secretion of saliva was reduced, the quality of life (QOL) related to the mouth would be heavily decreased, because of the increasing the risks of oral diseases and the dysfunctions of nutrition intake and difficulty in speaking. In this study, we proposed the means of maintaining good oral QOL by replacement therapy of artificial saliva in the patients with xerostomia, through analyzing the functions of saliva, preparing of artificial saliva, and developing the saliva-secreting automated device placed inside the mouth.

Free Research Field

口腔衛生学