The actual situation and the impact of cognitive problems on life in breast cancer patients receiving hormonal therapy

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670946
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Clinical nursing
• Research Institution: Osaka University
• Principal Investigator: MASUTANI Eiko 大阪大学, 医学(系)研究科(研究院), 講師 (70213759)
• Co-Investigator(Kenkyū-buntansha): ARAO Harue (50326302)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 認知機能低下 / 乳がん患者 / ホルモン療法

Outline of Final Research Achievements

The purpose of this study was to develop a "Subjective Cognitive Rating　Scale: SCRS" of breast cancer patients receiving hormonal therapy, and to clarify the actual subjective cognitive decline in breast cancer patients.
A scale draft was created along the steps of the scale development. A reliability and validity study in patients was conducted and 402 subjects　were analyzed. As a result, the scale's internal consistency and construction validity were confirmed.The subjects were divided into three groups by SCRS score: a ”high score group,” a ”middle score group,” a ”low score group.” In the high score group, the mean scores of symptoms, such as menopausal symptoms, fatigue, depression and anxiety were significantly higher. In addition, in the high score group, patients' QOL was decreased, and the actual condition of the patient's cognitive problems affecting their social life was revealed.

Free Research Field

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