2017 Fiscal Year Final Research Report
Sophisticate Design of Nano-Particular Type PET Probes for Qualitative Diagnosis and Theragnosis of Cancer
Project/Area Number |
25710011
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Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Partial Multi-year Fund |
Research Field |
Tumor diagnostics
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Research Institution | Institute of Physical and Chemical Research |
Principal Investigator |
Mukai Hidefumi 国立研究開発法人理化学研究所, ライフサイエンス技術基盤研究センター, ユニットリーダー (60570885)
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Project Period (FY) |
2013-04-01 – 2017-03-31
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Keywords | PETイメージング / がん / ナノ粒子 / セラグノーシス / 抗体 / ペプチド |
Outline of Final Research Achievements |
In vivo visualization of drug targets and disease-related molecules is essential for diagnosis and drug efficacy evaluation. To realize that, molecular probe development is a key. We developed novel approaches for the improvement of PET imaging contrast such as urokinase injection-triggered PET probe clearance enhancement system. These results could shorten the time required to obtain sufficient contrast and decrease patient radiation exposure.
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Free Research Field |
ドラッグデリバリー、分子イメージング
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