Proteomics analysis of cancer stem cell and its microenvironment using FFPE tissue and cancer cell line

2015 Fiscal Year Final Research Report

• Project/Area Number: 25710013
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Tumor diagnostics
• Research Institution: Shizuoka Cancer Center Research Institute
• Principal Investigator: Hatakeyama Keiichi 静岡県立静岡がんセンター(研究所), その他部局等, その他 (20564157)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: プロテオミクス解析 / 単一細胞解析 / がん

Outline of Final Research Achievements

This research aim is discovery of molecules for prognostic prediction using proteome analysis of cancer stem cell and its microenvironment. This approach focuses on analysis of formalin-fixed paraffin-embedded (FFPE) tissue and cancer cell line.
We identified proteins secreted from unique cell population in colorectal cancer. Furthermore, this achievement progressed a new research to analyze single cancer cell, resulting wining next grant-in-aid.

Free Research Field

腫瘍診断学