Understanding metabolic systems for human gut microbiome

2015 Fiscal Year Final Research Report

• Project/Area Number: 25710016
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Genome biology
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: Yamada Takuji 東京工業大学, 生命理工学研究科, 講師 (10437262)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: バイオインフォマティクス / メタゲノミクス / ヒト腸内細菌 / データベース

Outline of Final Research Achievements

Human gut harbors millions of microbiome, and their functional ability have wide diversity. Most of related works are based on KEGG database for their functional annotation, however, most of functional modules are not well known.
Here we developed the database for gut microbiome, called as “enteropathway”, allows researchers uncover functionality of gut microbiome more clearly.　For example, we suggested few modules have high diversity across 1000 individuals, showing the diverse metabolic potential. In addition, these novel defined modules are under represented in Obesity patients comparing with healthy individuals.

Free Research Field

バイオインフォマティクス