2016 Fiscal Year Final Research Report
Elucidation of alkaloid translocation mechanism in plants and application to metabolic engineering.
| Project/Area Number |
25712012
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Applied biochemistry
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| Research Institution | Kobe Pharmaceutical University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | アルカロイド / 輸送 / 植物 / タバコ / ニコチン / MATE / トランスポーター |
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| Outline of Final Research Achievements |
Plants produce various metabolites including secondary metabolite, such as alkaloids, to adapt to their environment. Most secondary alkaloids are stored in a particular organelle of a specific organ, however, our knowledge of transport mechanism is limited. In this study, we investigated nicotine translocation mechanism from roots to leaves in Nicotiana tabacum. We identified and characterized some transporters, i.e., JAT1, JAT2, and NUP1. These transporters are related to nicotine transport, biosynthesis, and defense mechanism in tobacco. Application of these new knowledge to metabolic engineering might be useful for high production of valuable compounds in future.
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| Free Research Field |
植物細胞分子生物学
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