2015 Fiscal Year Final Research Report
Novel topical device for atopic dermatitis through the skin barrier protection and the anti-inflammatory effect
| Project/Area Number |
25750156
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 炎症抑制 / アトピー性皮膚炎 / 医療機器 |
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| Outline of Final Research Achievements |
Atopic dermatitis (AD) is a common inflammatory disease of the skin, which is characterized by xerosis, pruritus, and erythematous lesions. AD arises as a result of the interaction between environmental and genetic factors. Especially, epidermal barrier dysfunction caused by genetic barrier defects is a primary event in the development of AD. In this study, we planned to develop the novel topical device which had the skin barrier protection and anti-inflammatory effect, consisting of candidate material A and B, and evaluated the efficacy of this device using the model mouse which exhibited AD-like lesions.
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| Free Research Field |
生体医工学
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