Oxidative stress markers for rehabilitation on patients with mechanical ventilation

2016 Fiscal Year Final Research Report

• Project/Area Number: 25750204
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Hiroshima University
• Principal Investigator: Taito Shunsuke 広島大学, 病院(医), 理学療法士 (50613501)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 人工呼吸患者 / 酸化ストレス / リハビリテーション / 離床

Outline of Final Research Achievements

We examined pulmonary oxidative stress in cigarette smokers and non-smokers as preliminary study in order to clarify the effect of rehabilitation on pulmonary oxidative stress in patients with mechanical ventilation. We chose hydrogen peroxide concentrations in exhaled breath condensate as oxidative stress markers. The study suggested that moderate-intensity exercise did not induce pulmonary oxidative stress in cigarette smokers. We examined the change of hydrogen peroxide concentrations in exhaled breath condensate after rehabilitation in patients with mechanical ventilation. The results suggested that rehabilitation induced pulmonary oxidative stress in patients with mechanical ventilation.

Free Research Field

リハビリテーション