2015 Fiscal Year Final Research Report
The mechanisms by which physical exercise regulates insulin action in liver
| Project/Area Number |
25750337
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Sports science
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| Research Institution | Niigata University of Health and Welfare |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 肝臓 / 熱刺激 / ヘパトカイン / 身体運動 / インスリン作用 |
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| Outline of Final Research Achievements |
Regular physical exercise enhances insulin action not only in exercised muscles but also in liver. However, it not clear the mechanisms by which exercise regulates liver adaptations.
In this study, I have revealed that repeated heat stimulation on rat hindlimbs, with heat diffusion to liver, led to adaptations in the liver as observed in regularly exercised subjects. This result indicates that heat production in exercised muscle and its diffusion to liver have important role in liver adaptations in response to exercise.
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| Free Research Field |
運動生理学・運動生化学
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