2014 Fiscal Year Final Research Report
The effects of continuous exercise training on age-related impairment of oral immunity
| Project/Area Number |
25750358
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 免疫機能 / 運動 / 加齢 |
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| Outline of Final Research Achievements |
The purpose of this study was to examine the effects of continuous exercise training on age-related impairment of oral immunity. Mouse beta-defensin 3 (mBD3) expression in salivary gland did not show significant change after the acute exhaustive exercise. There was no significant difference between aged and control mice in mBD3 expression in salivary gland. 8 weeks of voluntary wheel running significantly decreased mBD3 expression in salivary gland in aged mice. Consequently, mBD3 in salivary gland might be not influenced by aging, and response to exercise. Future study needs to examine the effects of aging and exercise on mBD3 by using more sample size and treadmill, which controls intensity and volume of exercise.
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| Free Research Field |
スポーツ医学
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