Development of catalytic carbon-carbon bond forming reaction for making quaternary carbon with using organoborate salt

2014 Fiscal Year Final Research Report

• Project/Area Number: 25810024
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Organic chemistry
• Research Institution: Osaka Prefecture University
• Principal Investigator: UEDA Mitsuhiro 大阪府立大学, 理学(系)研究科(研究院), 助教 (60566298)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 鈴木ー宮浦クロスカップリング反応 / 有機ボロン酸 / プロパルギルアセテート / 遷移金属非存在下 / カルボカチオン

Outline of Final Research Achievements

The transition-metal catalyzed cross-coupling reaction with using organoboronic acids provides a magnificent tool for organic synthesis. With this method, we generally rely on the use of precious transition metals, such as palladium complexes, as the catalyst. In this time, we found that cross-coupling reaction of propargylic acetates with organoboronic acids proceeded to give the corresponding acetylenic products under metal-free conditions.

Free Research Field

有機化学