2014 Fiscal Year Final Research Report
The role of alpha2-antiplasmin in memory formation and dendritic growth
| Project/Area Number |
25830057
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | Doshisha Women's College of Liberal Arts |
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Principal Investigator |
KAWASHITA Eri 同志社女子大学, 薬学部, 助教 (80509266)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | α2-antiplasmin / 記憶 / 樹状突起 / 神経細胞 |
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| Outline of Final Research Achievements |
We found that α2-Antiplasmin (α2AP) is a crucial mediator of cognitive function. We also demonstrated that α2AP induces dendritic growth in hippocampal neurons through p38 MAPK activation, independent of plasmin.
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| Free Research Field |
神経科学
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