2014 Fiscal Year Final Research Report
Visualization of the whole metabolic network through absolute protein quantification
| Project/Area Number |
25830143
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
System genome science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 定量プロテオミクス / 代謝ネットワーク / 絶対量ベース代謝システム解析 |
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| Outline of Final Research Achievements |
In this project, I focused on an absolute quantification of metabolic enzymes in each mouse organ and analyzing metabolic network for a comprehensive understanding of the metabolic system in individual level. I optimized the method for absolute protein quantification with our information-based quantitative proteomics technique and developed a novel mathematical method “Absolute quantity-based metabolic systems analysis (AMSA)”, which provides integrated analysis of metabolic network in each mouse organ.
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| Free Research Field |
定量生物学
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