2015 Fiscal Year Final Research Report
Model of mRNA transcription and transcriptional factor binding
| Project/Area Number |
25830148
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
System genome science
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
NIKAIDO Itoshi 国立研究開発法人理化学研究所, 情報基盤センター, ユニットリーダー (00383290)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | バイオインフォマティクス |
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| Outline of Final Research Achievements |
Functions of cell are defined by temporal and special regulations of transcriptional networks in our body. Recently, massively parallel DNA sequencer realizes that we easily measure global gene expressions and binding of transcriptional factors on a genomic DNA. However, researchers had carried out simple integration of mRNA quantity and transcription factor binding to understand a transcriptional regulation. Thus, I study to develop statistical and physical models of mRNA transcription for quantitative description and understanding of transcriptional networks.
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| Free Research Field |
バイオインフォマティクス
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