2015 Fiscal Year Final Research Report
Exploration of Golgi casein kinases
Project/Area Number |
25840031
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Functional biochemistry
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Research Institution | Chiba University |
Principal Investigator |
Ishikawa Hiroyuki 千葉大学, 理学(系)研究科(研究院), 准教授 (00398819)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Keywords | ゴルジ体キナーゼ / リン酸化 |
Outline of Final Research Achievements |
Casein is a secretory phosphorylated protein containing in milk. We attempted to identify the kinase molecule to phosphorylate casein in the Golgi. As a result, we identified candidate genes for novel Golgi kinases in the Drosophila genome. We also succeeded in producing Drosophila mutants of these genes. Further, we found that overexpression of a Golgi kinase FAM20C affected the normal development of Drosophila.
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Free Research Field |
機能生物化学
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