2015 Fiscal Year Final Research Report
Mechanism to maintain pluripotency of the mouse epiblast via Nodal signaling.
| Project/Area Number |
25840087
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Developmental biology
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| Research Institution | Kyushu University |
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Principal Investigator |
Oki Shinya 九州大学, 医学(系)研究科(研究院), 助教 (90452713)
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| Co-Investigator(Renkei-kenkyūsha) |
MENO Chikara 九州大学, 大学院医学研究院, 教授 (20311764)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | Nodal / エピブラスト / 中胚葉誘導 / 原条形成 / 多分化能 / ChIP-seq |
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| Outline of Final Research Achievements |
This study identified the genes directly regulated by Nodal signaling in the mouse epiblast, particularly involved in the pluripotency, differentiation into the neural epithelium, and primitive streak formation. This study also developed a software and database that are useful to exploit published ChIP-seq data.
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| Free Research Field |
発生学、バイオインフォマティクス
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